Structure via PubChem · Public domain (PubChem)
تیلماکوکسیب
Sign in to saveAlso known as RWJ-57504, 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo(4,5)imidazo(1,2a)pyridine-4-N-(2-fluorophenyl)carboxamide, JTP-19605, JTE-522, 4-(4-cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide
Tilmacoxib or JTE-522 is a COX-2 inhibitor and is an effective chemopreventive agent against rat experimental liver fibrosis.
Chemical data
- Formula
- C16H19FN2O3S
- Molecular weight
- 338.4 g/mol
- IUPAC name
- 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide
- SMILES
- CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)F)C3CCCCC3
- InChIKey
- MIMJSJSRRDZIPW-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 94.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 338.110042
Show 5 more facts
- canonical SMILES
- CC1=NC(=C(O1)C2=CC(=C(C=C2)S(=O)(=O)N)F)C3CCCCC3
- chemical formula
- C₁₆H₁₉FN₂O₃S
- World Health Organisation international non-proprietary name
- tilmacoxib
- Commons category
- Tilmacoxib
- subject has role
- COX-2 inhibitor
via Wikidata · CC0