tioconazole
Sign in to saveAlso known as Trosyl, TZ-3, UK-20349, Vagistat-1, Vagistat, Tioconazol, Tioconazolum
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 415485693
- Drug.IUPAC_name
- (RS)-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
- Drug.image
- Tioconazole.svg
- Drug.image_class
- skin-invert-image
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Vagistat-1, 1-Day
- Drug.legal_US
- OTC
- Drug.routes_of_administration
- Topical
- Drug.CAS_number
- 65899-73-2
- Drug.ATC_prefix
- D01
- Drug.ATC_suffix
- AC07
- Drug.PubChem
- 5482
- Drug.DrugBank
- DB01007
- Drug.ChemSpiderID
- 5282
- Drug.UNII
- S57Y5X1117
- Drug.KEGG
- D00890
- Drug.ChEBI
- 9604
via Wikipedia infobox
Research
267 papers- Tioconazole.2006
- Tioconazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses.Drugs · 1986
- Tioconazole exerts anti-TB activity by destroying cell integrity.European journal of pharmacology · 2025
- Combined fractional CO2 laser with topical tioconazole versus Q-switched Nd-YAG laser in the treatment of onychomycosis; a randomized comparative trial.Lasers in medical science · 2024
- Cytotoxic mechanism of tioconazole involves cell cycle arrest at mitosis through inhibition of microtubule assembly.Cytotechnology · 2022
via PubMed
Wikidata facts
- Mass
- 385.981
Show 5 more facts
- Commons category
- Tioconazole
- chemical formula
- C₁₆H₁₃Cl₃N₂OS
- canonical SMILES
- C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
- defined daily dose
- 0.3
- MCN code
- 2934.99.54
Sources (3)
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Side effects
- Synthesis
- References
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.
Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".