tioconazole
Sign in to saveAlso known as Trosyl, TZ-3, UK-20349, Vagistat-1, Vagistat, Tioconazol, Tioconazolum
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 415485693
- Drug.IUPAC_name
- (RS)-1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
- Drug.image
- Tioconazole.svg
- Drug.image_class
- skin-invert-image
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Vagistat-1, 1-Day
- Drug.legal_US
- OTC
- Drug.routes_of_administration
- Topical
- Drug.CAS_number
- 65899-73-2
- Drug.ATC_prefix
- D01
- Drug.ATC_suffix
- AC07
- Drug.PubChem
- 5482
- Drug.DrugBank
- DB01007
- Drug.ChemSpiderID
- 5282
- Drug.UNII
- S57Y5X1117
- Drug.KEGG
- D00890
- Drug.ChEBI
- 9604
via Wikipedia infobox
Research
267 papers- Tioconazole.2006
- Tioconazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses.Drugs · 1986
- Tioconazole exerts anti-TB activity by destroying cell integrity.European journal of pharmacology · 2025
- Combined fractional CO2 laser with topical tioconazole versus Q-switched Nd-YAG laser in the treatment of onychomycosis; a randomized comparative trial.Lasers in medical science · 2024
- Cytotoxic mechanism of tioconazole involves cell cycle arrest at mitosis through inhibition of microtubule assembly.Cytotechnology · 2022
via PubMed
Wikidata facts
- Subclass of
- azole
- Mass
- 385.981
- Has use
- medication
Show 6 more facts
- Commons category
- Tioconazole
- chemical formula
- C₁₆H₁₃Cl₃N₂OS
- medical condition treated
- vulvovaginal candidiasis
- canonical SMILES
- C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
- defined daily dose
- 0.3
- MCN code
- 2934.99.54
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Side effects
- Synthesis
- References
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by a fungus or yeast. It is marketed under the brand names Trosyd and Gyno-Trosyd (Pfizer, later Johnson & Johnson and now Kenvue). Tioconazole ointments serve to treat women's vaginal yeast infections. They are available in one day doses, as opposed to the 7-day treatments commonly used in the past.
Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Excerpted from Wikipedia’s “tioconazole” article, available under the CC BY-SA 4.0 licence.