TLR9

Name

toll like receptor 9

Type

protein-coding

Position

52,221,080–52,225,651 (−)

Aliases

CD289

Ensembl

ENSG00000239732

RefSeq RNA

NM_017442.4, NM_138688.1

RefSeq protein

NP_059138.1

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017].

via MyGene.info

Gene · Ensembl

toll like receptor 9

Symbol

TLR9

Biotype

Protein coding

Organism

Homo sapiens

Location

3:52,221,080-52,225,651

Strand

Reverse (−)

Assembly

GRCh38