Structure via PubChem · Public domain (PubChem)
triazolam
Sign in to saveAlso known as U-33030, Halcion, Triazolamum
Triazolam, sold under the brand name Halcion among others, is a central nervous system (CNS) depressant tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepine (BZD) derivatives. It possesses pharmacological properties similar to those of other benzodiazepines, but it is generally only used as a sedative to treat severe insomnia. In addition to the hypnotic properties, triazolam's amnesic, anxiolytic, sedative, anticonvulsant, and muscle relaxant properties are pronounced as well.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458459564
- Drug.image
- Triazolam.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 160
- Drug.image2
- Triazolam ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Halcion, others
- Drug.MedlinePlus
- a684004
- Drug.DailyMedID
- Triazolam
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- CD05
- Drug.legal_AU
- S4
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule IV
- Drug.legal_DE
- Rx-only/Anlage III
via Wikipedia infobox
Chemical data
- Formula
- C17H12Cl2N4
- Molecular weight
- 343.2 g/mol
- IUPAC name
- 8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine
- SMILES
- CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
- InChIKey
- JOFWLTCLBGQGBO-UHFFFAOYSA-N
- XLogP
- 2.4
- Polar surface area
- 43.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
1,857 papers- Triazolam treatment controversy.The Annals of pharmacotherapy · 1994
- Zolpidem: distinct from triazolam?The Annals of pharmacotherapy · 1997
- New drug evaluations. Triazolam.Drug intelligence & clinical pharmacy · 1983
- Triazolam.Lancet (London, England) · 1991
- Triazolam.Lancet (London, England) · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 342.044
- Has use
- medication
Show 7 more facts
- subject has role
- benzodiazepine drug
- chemical formula
- C₁₇H₁₂Cl₂N₄
- canonical SMILES
- CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
- Commons category
- Triazolam
- MCN code
- 2933.91.83
- defined daily dose
- 0.25
- legal status (medicine)
- boxed warning
Sources (6)
via Wikidata · CC0
~4 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Side effects
- Tolerance, dependence, and withdrawal
- Contraindications
- Elderly
- Interactions
- Overdose
- Pharmacology
- Society and culture
- Recreational use
- Legal status
- Brand names
- References
Triazolam, sold under the brand name Halcion among others, is a central nervous system (CNS) depressant tranquilizer of the triazolobenzodiazepine (TBZD) class, which are benzodiazepine (BZD) derivatives. It possesses pharmacological properties similar to those of other benzodiazepines, but it is generally only used as a sedative to treat severe insomnia. In addition to the hypnotic properties, triazolam's amnesic, anxiolytic, sedative, anticonvulsant, and muscle relaxant properties are pronounced as well.
Triazolam was initially patented in 1970 and went on sale in the United States in 1982. In 2017, it was the 289th most commonly prescribed medication in the United States, with more than one million prescriptions.
Excerpted from Wikipedia’s “triazolam” article, available under the CC BY-SA 4.0 licence.