tromantadine

Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir.

Chemical data

Formula: C16H28N2O2
Molecular weight: 280.41 g/mol
IUPAC name: N-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide

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Research

54 papers

Tromantadine: inhibitor of early and late events in herpes simplex virus replication.Antimicrobial agents and chemotherapy · 1982
Tromantadine inhibits a late step in herpes simplex virus type 1 replication and syncytium formation.Antiviral research · 1990
The metabolism of tromantadine.Biomedical mass spectrometry · 1985
[Contact allergy to tromantadine].Dermatosen in Beruf und Umwelt. Occupation and environment · 1984
Contact balanitis to tromantadine.Clinical and experimental dermatology · 2016

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Wikidata facts

Subclass of: chemical compound
Mass: 280.215

Show 4 more facts

chemical formula: C₁₆H₂₈N₂O₂
route of administration: topical medication
canonical SMILES: CN(C)CCOCC(=O)NC12CC3CC(C1)CC(C3)C2
Commons category: Tromantadine

Sources (2)

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Encyclopedic overview

3 sections

Contents

Mechanism
References
External links

Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir.

Like rimantadine, amantadine, and adapromine, tromantadine is a derivative of adamantane.

Excerpted from Wikipedia’s “tromantadine” article, available under the CC BY-SA 4.0 licence.

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