تریپتولین
Sign in to saveTryptoline, also known as tetrahydro-β-carboline and tetrahydronorharmane, is a natural organic derivative of β-carboline. It is an alkaloid chemically related to tryptamines. Derivatives of tryptoline have a variety of pharmacological properties and are known collectively as tryptolines.
Research
250 papers- Multi-tiered chemical proteomic maps of tryptoline acrylamide-protein interactions in cancer cells.Nature chemistry · 2024
- Tryptoline Stereoprobe Elaboration Identifies Inhibitors of the GRPEL1-HSPA9 Chaperone Complex.bioRxiv : the preprint server for biology · 2025
- Tryptoline-based benzothiazoles re-sensitize MRSA to β-lactam antibiotics.Bioorganic & medicinal chemistry · 2019
- Algicidal effect of tryptoline against Microcystis aeruginosa: Excess reactive oxygen species production mediated by photosynthesis.The Science of the total environment · 2022
- Tryptoline formation by a preparation from brain with 5-methyltetrahydrofolic acid and tryptamine.Science (New York, N.Y.) · 1975
via PubMed
Wikidata facts
- Mass
- 172.1
Show 5 more facts
- chemical formula
- C₁₁H₁₂N₂
- subject has role
- neurotoxin
- canonical SMILES
- C1CNCC2=C1C3=CC=CC=C3N2
- found in taxon
- Phalaris coerulescens
- Commons category
- Tryptoline
Sources (2)
via Wikidata · CC0