4-HO-pyr-T, also known as '4-hydroxy-N,N-tetramethylenetryptamine', is a serotonin receptor modulator of the tryptamine, 4-hydroxytryptamine, and pyrrolidinylethylindole families. It is the 4-hydroxyl analogue of pyr-T and the analogue of psilocin (4-HO-DMT) and 4-HO-DET in which the N,N-dialkyl moiety has been cyclized into a pyrrolidine ring.
4-HO-pyr-T, also known as '4-hydroxy-N,N-tetramethylenetryptamine', is a serotonin receptor modulator of the tryptamine, 4-hydroxytryptamine, and pyrrolidinylethylindole families. It is the 4-hydroxyl analogue of pyr-T and the analogue of psilocin (4-HO-DMT) and 4-HO-DET in which the N,N-dialkyl moiety has been cyclized into a pyrrolidine ring.
==Use and effects== In his book TiHKAL (Tryptamines I Have Known and Loved), Shulgin gives the dose as ≥20mg orally, its duration as unknown, and its onset as about 3hours. It was described as quite unlike psilocin and bordering on bizarre. There were minimal visual disturbances and no alterations in colors or objects. It was however said to heighten the intellectual process. The drug was said to be more "stimulant-like" than hallucinogenic or psychedelic. 4-HO-pyr-T was described as very unpleasant.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).