UBE2B
Sign in to saveAlso known as E2-17kDa, HHR6B, HR6B, RAD6B, UBC2, ubiquitin conjugating enzyme E2 B
Ubiquitin-conjugating enzyme E2 B is a protein that in humans is encoded by the UBE2B gene.
Gene data
UBE2B- Name
- ubiquitin conjugating enzyme E2 B
- Type
- protein-coding
- Aliases
- E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein UBE2B PDB 1jas.png
Show 5 more facts
- HomoloGene ID
- 101298
- exact match
- identifiers.org/ncbigene/7320
- genomic end
- 134392108
- genomic start
- 134371184
- cytogenetic location
- 5q31.1
Sources (4)
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Ubiquitin-conjugating enzyme E2 B is a protein that in humans is encoded by the UBE2B gene.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.