UBE2E1
Sign in to saveAlso known as UBCH6, ubiquitin conjugating enzyme E2 E1
Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.
Gene data
UBE2E1- Name
- ubiquitin conjugating enzyme E2 E1
- Type
- protein-coding
- Position
- 23,805,907–23,892,208 (+)
- Aliases
- UBCH6
- Ensembl
- ENSG00000170142
- RefSeq RNA
- NM_001202476.2, NM_003341.5, NM_182666.3, XM_005265431.6, XM_054347737.1
- RefSeq protein
- NP_001189405.1, NP_003332.1, NP_872607.1, XP_005265488.1, XP_054203712.1
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ubiquitin conjugating enzyme E2 E1
- Symbol
- UBE2E1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:23,805,907-23,892,208
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein UBE2E1 PDB 1y6l.png
Show 7 more facts
- HomoloGene ID
- 84372
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7324
- genomic end
- 23891640
- genomic start
- 23805955
- chromosome
- human chromosome 3
- cytogenetic location
- 3p24.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.
== Function ==
Excerpted from Wikipedia’s “UBE2E1” article, available under the CC BY-SA 4.0 licence.