WIF1

Also known as WIF-1, WNT inhibitory factor 1

Wnt inhibitory factor 1 is a protein that in humans is encoded by the WIF1 gene. WIF1 is a lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling.

Gene data

WIF1

Name: Wnt inhibitory factor 1
Type: protein-coding
Aliases: WIF-1

The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010].

via MyGene.info

Wikidata facts

Image: Protein WIF1 PDB 2d3j.png

Show 5 more facts

HomoloGene ID: 31430
exact match: identifiers.org/ncbigene/11197
genomic end: 65121305
genomic start: 65444406
cytogenetic location: 12q14.3

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Wnt inhibitory factor 1 is a protein that in humans is encoded by the WIF1 gene. WIF1 is a lipid-binding protein that binds to Wnt proteins and prevents them from triggering signalling.

== Function ==