EC 2.7.1

thumb|upright=1.25|Dihydroxyacetone kinase in complex with a non-hydrolyzable ATP analog (AMP-PNP). Coordinates from PDB ID:1UN9.

A hexokinase is an enzyme that irreversibly phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate for hexokinases, and glucose-6-phosphate is the most important product. Hexokinase possesses the ability to transfer an inorganic phosphate group from ATP to a substrate.

class of enzymes

Phosphofructokinase (PFK) is a kinase enzyme that phosphorylates fructose 6-phosphate in glycolysis.

Glucokinase () is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase is expressed in cells of the liver and pancreas of humans and most other vertebrates. In each of these organs it plays an important role in the regulation of carbohydrate metabolism by acting as a glucose sensor, triggering shifts in metabolism or cell function in response to rising or falling levels of glucose, such as occur after a meal or when fasting. Mutations of the gene for this enzyme can cause unusual forms of diabetes or hypoglycemia.

enzyme found in most living cells

class of enzymes

Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP. Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of α-D-galactose to glucose 1-phosphate. First isolated from mammalian liver, galactokinase has been studied extensively in yeast, archaea, plants, and humans.

class of enzymes, phosphotransferases that catalyze the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate

class of enzymes

mammalian protein found in Homo sapiens

Fructokinase (/fruc•to•ki•nase/ [-ki´nas]), also known as D-fructokinase or D-fructose (D-mannose) kinase, is an enzyme () of the liver, intestine, and kidney cortex. Fructokinase is in a family of enzymes called transferases, meaning that this enzyme transfers functional groups; it is also considered a phosphotransferase (or, frequently, a kinase) since it specifically transfers a phosphate group. Fructokinase specifically catalyzes the transfer of a phosphate group from adenosine triphosphate (ATP, the substrate) to fructose as the initial step in its utilization. The main role of fructokina

class of enzymes

InterPro Family

protein-coding gene in the species Homo sapiens

The phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (the HUGO-approved official symbol = PIK3CA; HGNC ID, HGNC:8975), also called p110α protein, is a class I PI 3-kinase catalytic subunit. The human p110α protein is encoded by the PIK3CA gene.

class of enzymes

protein-coding gene in the species Homo sapiens

class of enzymes

class of enzymes

Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene.

class of enzymes

In enzymology, a triokinase () is an enzyme that catalyzes the chemical reaction

class of enzymes

class of enzymes

Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma is an enzyme in humans that is encoded by the PIP4K2C gene. It is one of the phosphatidylinositol 4-phosphate 5-kinases.

class of enzymes

class of enzymes

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.

In enzymology, a gluconokinase () is an enzyme that catalyzes the chemical reaction

class of enzymes

class of enzymes

protein-coding gene in the species Homo sapiens

class of enzymes

In enzymology, a ribulokinase () is an enzyme that catalyzes the chemical reaction

Phosphoribulokinase (PRK) () is an essential photosynthetic enzyme that catalyzes the ATP-dependent phosphorylation of ribulose 5-phosphate (RuP) into ribulose 1,5-bisphosphate (RuBP), both intermediates in the Calvin Cycle. Its main function is to regenerate RuBP, which is the initial substrate and CO2-acceptor molecule of the Calvin Cycle. PRK belongs to the family of transferase enzymes, specifically those transferring phosphorus-containing groups (phosphotransferases) to an alcohol group acceptor. Along with ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCo), phosphoribulokinase is

InterPro Family

L-Fuculokinase () is an enzyme that catalyzes the chemical reaction

protein-coding gene in the species Homo sapiens

class of enzymes

In enzymology, a 2-dehydro-3-deoxygluconokinase () is an enzyme that catalyzes the chemical reaction

Phosphatidylinositol 4-kinase alpha is an enzyme that in humans is encoded by the PI4KA gene.

In enzymology, a 2-dehydro-3-deoxygalactonokinase () is an enzyme that catalyzes the chemical reaction

InterPro Family

class of enzymes