Also known as entrez:1633, deoxycytidine kinase
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, DCK is referenced by 406 other articles, and connects out to nucleotide, PubMed and Ensembl genome database project.
Vinony files it under EC 2.7.1 and Genes on human chromosome 4.
Its subject is documented across 6 Wikipedia language editions.
Gene data
DCK- Name
- deoxycytidine kinase
- Type
- protein-coding
- Position
- 70,992,538–71,030,914 (+)
- Ensembl
- ENSG00000156136
- RefSeq RNA
- NM_000788.3, XM_047449689.1, XM_054349068.1
- RefSeq protein
- NP_000779.1, XP_047305645.1, XP_054205043.1
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
deoxycytidine kinase
- Symbol
- DCK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:70,992,538-71,030,914
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein DCK PDB 1p5z.png
Show 8 more facts
- HomoloGene ID
- 616
- genomic end
- 71896631
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1633
- genomic start
- 71858255
- chromosome
- human chromosome 4
- cytogenetic location
- 4q13.3
- expressed in
- ganglionic eminence
via Wikidata · CC0