Structure via PubChem · Public domain (PubChem)
1,10-phenanthroline
Sign in to saveAlso known as phen, ortho-phenanthroline, orthophenanthroline, o-phenanthroline
1,10-Phenanthroline (phen) is a heterocyclic organic compound. It is a white solid that is soluble in organic solvents. The 1,10 refers to the location of the nitrogen atoms that replace CH's in the hydrocarbon called phenanthrene.
Chemical data
- Formula
- C12H8N2
- Molecular weight
- 180.2 g/mol
- IUPAC name
- 1,10-phenanthroline
- SMILES
- C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1
- InChIKey
- DGEZNRSVGBDHLK-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 25.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
8,643 papers- 1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient.EMBO reports · 2024
- Zinc trafficking: 1,10-phenanthroline, glutathione, and other metal binding ligands form adducts with proteomic Zn2.Metallomics : integrated biometal science · 2023
- 1,10-Phenanthroline-H2O2-KSCN-CuSO4-NaOH oscillating chemiluminescence system.Luminescence : the journal of biological and chemical luminescence · 2009
- Antitumor Activity of 2,9-Di-Sec-Butyl-1,10-Phenanthroline.PloS one · 2016
- (N-{[4-(1,3-benzothiazol-2-yl)anilino]carbonylmethyl-kappaO}iminodiacetato-kappa(3)O,N,O')(1,10-phenanthroline-kappa(2)N,N')cobalt(II) pentahydrate.Acta crystallographica. Section C, Crystal structure communications · 2008
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Has part
- carbon
- Mass
- 180.069
- Image
- Phenanthroline.JPG
Show 6 more facts
- topic's main category
- Category:Phenanthrolines
- subject has role
- protease inhibitor
- chemical formula
- C₁₂H₈N₂
- Commons category
- Phenanthroline
- canonical SMILES
- C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1
- melting point
- 118
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Synthesis
- Reactions
- Pharmacology
- References
1,10-Phenanthroline (phen) is a heterocyclic organic compound. It is a white solid that is soluble in organic solvents. The 1,10 refers to the location of the nitrogen atoms that replace CH's in the hydrocarbon called phenanthrene.
Abbreviated "phen", or sometimes "o-phen" for ortho-phenanthroline, it is used as a ligand in coordination chemistry, forming strong complexes with most metal ions. It is often sold as the monohydrate.
Excerpted from Wikipedia’s “1,10-phenanthroline” article, available under the CC BY-SA 4.0 licence.