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pheneturide
Sign in to saveAlso known as Ethylphenacemide
Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. Conceptually, it can be formed in the body as a metabolic degradation product from phenobarbital. It is considered to be obsolete and is now seldom used. It is marketed in Europe, including in Poland, Spain and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide. As such, it is only used in cases of severe epilepsy when other, less-toxic dr
Chemical data
- Formula
- C11H14N2O2
- Molecular weight
- 206.24 g/mol
- IUPAC name
- N-carbamoyl-2-phenylbutanamide
- SMILES
- CCC(C1=CC=CC=C1)C(=O)NC(=O)N
- InChIKey
- AJOQSQHYDOFIOX-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 72.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- epilepsy
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 206.106
Show 4 more facts
- chemical formula
- C₁₁H₁₄N₂O₂
- canonical SMILES
- CCC(C1=CC=CC=C1)C(=O)NC(=O)N
- subject has role
- anticonvulsant agent
- medical condition treated
- epilepsy
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride), also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class. Conceptually, it can be formed in the body as a metabolic degradation product from phenobarbital. It is considered to be obsolete and is now seldom used. It is marketed in Europe, including in Poland, Spain and the United Kingdom. Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide. As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed. Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.
== See also == Phenacemide
Excerpted from Wikipedia’s “pheneturide” article, available under the CC BY-SA 4.0 licence.