5-Hydroxyuracil
Sign in to saveAlso known as Dihydropyrimidine-2,4,5(3H)-trione, Isobarbituric acid
5-Hydroxyuracil is an oxidized form of cytosine that is produced by the oxidative deamination of cytosines by reactive oxygen species. It does not distort the DNA molecule and is bypassed by replicative DNA polymerases. It can miscode for adenine and is potentially mutagenic.
Wikidata facts
- Mass
- 128.022
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- chemical formula
- C₄H₄N₂O₃
- canonical SMILES
- C1=C(C(=O)NC(=O)N1)O
- Commons category
- 5-Hydroxyuracil
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5-Hydroxyuracil is an oxidized form of cytosine that is produced by the oxidative deamination of cytosines by reactive oxygen species. It does not distort the DNA molecule and is bypassed by replicative DNA polymerases. It can miscode for adenine and is potentially mutagenic.
==References==
Connections
International Standard Book Number
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digital object identifier
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chemical formula
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molar mass
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cytosine
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Q180686
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CAS Registry Number
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PubChem
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DNA polymerase
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simplified molecular input line entry specification
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chemical nomenclature
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Q2311683
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International Chemical Identifier
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deamination
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European Chemicals Agency
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ChEBI
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standard state
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reactive oxygen species
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European Community number
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Jmol
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