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استیل دی هیدروکدئین

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EntityQ4673302· pop 11· linked from 892 articles

استیل دی هیدروکدئین

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Also known as dihydrothebacone, dihydrocodeine 6-acetate

Acetyldihydrocodeine is an opiate derivative discovered in Germany in 1914 and was used as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Acetyldihydrocodeine is a very close relative derivative of thebacon, where only the 6-7 bond is unsaturated. Acetyldihydrocodeine can be described as the 6-acetyl derivative of dihydrocodeine and is metabolised in the liver by demethylation and deacetylation to produce dihydromorphine.

Chemical data

Formula
C20H25NO4
Molecular weight
343.4 g/mol
IUPAC name
[(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate

via PubChem

Wikidata facts

Mass
343.17835828
Show 6 more facts
chemical formula
C₂₀H₂₅NO₄
Commons category
Acetyldihydrocodeine
isomeric SMILES
CC(=O)O[C@H]1CC[C@H]2[C@H]3Cc4ccc(c5c4[C@]2([C@H]1O5)CCN3C)OC
canonical SMILES
CC(=O)OC1CCC2C3CC4=C5C2(C1OC5=C(C=C4)OC)CCN3C
defined daily dose
30
subject has role
opioid
Sources (3)

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