ACTG2
Sign in to saveAlso known as ACT, ACTA3, ACTE, ACTL3, ACTSG, VSCM, actin, gamma 2, smooth muscle, enteric, actin gamma 2, smooth muscle
Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene.
Gene data
ACTG2- Name
- actin gamma 2, smooth muscle
- Type
- protein-coding
- Position
- 73,892,232–73,919,865 (+)
- Aliases
- ACT, ACTA3, ACTE, ACTL3, ACTSG, MMIHS5, VSCM, VSCM1
- Ensembl
- ENSG00000163017
- RefSeq RNA
- NM_001199893.2, NM_001615.4
- RefSeq protein
- NP_001186822.1, NP_001606.1
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
actin gamma 2, smooth muscle
- Symbol
- ACTG2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:73,892,232-73,919,865
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PBB Protein ACTA1 image.jpg
Show 8 more facts
- HomoloGene ID
- 123845
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/72
- genomic end
- 74146992
- genomic start
- 74119441
- expressed in
- urethra
- chromosome
- human chromosome 2
- cytogenetic location
- 2p13.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene.
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.
Excerpted from Wikipedia’s “ACTG2” article, available under the CC BY-SA 4.0 licence.