File:Actin_with_ADP_highlighted.png · Wikimedia Commons · See Wikimedia Commons
actina
Sign in to saveAlso known as actins, Actin family, Actin, IPR004000
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm.
Actin is a protein found in nearly all living cells that assembles into tiny filaments that make up part of the cell's internal structural framework and form the thin filaments in muscle tissue. Because actin is so abundant and versatile, it plays essential roles in cell movement, shape changes, and muscle contraction.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Protein family.Symbol
- Actin
- Protein family.Name
- Actin
- Protein family.image
- Actin with ADP highlighted.png
- Protein family.caption
- Ribbon diagram of G-actin. ADP bound to actin's active site (multi color sticks near center of figure) as well as a complexed calcium dication (green sphere) are highlighted.
- Protein family.Pfam
- PF00022
- Protein family.InterPro
- IPR004000
- Protein family.PROSITE
- PDOC00340
- Protein family.SCOP
- 2btf
via Wikipedia infobox
Research
151,797 papers- Actin structure and function.Annual review of biophysics · 2011
- Actin and Actin-Binding Proteins.Cold Spring Harbor perspectives in biology · 2016
- Actin Mutations and Their Role in Disease.International journal of molecular sciences · 2020
- Actin's C-terminus coordinates actin structural changes and functions.Cytoskeleton (Hoboken, N.J.) · 2023
- Actin cytoskeleton and sperm function.Biochemical and biophysical research communications · 2018
via PubMed
Wikidata facts
- Instance of
- protein family
- Image
- Actin with ADP highlighted.png
Show 3 more facts
- Commons category
- Actin
- physically interacts with
- adenosine triphosphate
- different from
- actinium
Sources (6)
via Wikidata · CC0
Article · Italiano
L'Actina è una proteina di forma globulare, con un diametro di circa 7 nanometri, dal peso di 43 kiloDalton (kDa) e costituisce una porzione abbondante (5-10%) di tutte le proteine delle cellule eucariote. La più alta presenza di actina si verifica nelle cellule del tessuto muscolare (circa 20% delle proteine totali), dove è fondamentale per il processo di contrazione. Ogni singola subunità di actina (detta actina G, cioè globulare) si può legare ad altre due subunità, formando così un polimero lineare. Due polimeri lineari avvolti tra di loro danno origine ad un microfilamento, uno dei tre tipi fondamentali di filamenti che compongono il citoscheletro. Nei vertebrati sono state identificate tre diverse isoforme di actina: , e .
Abstract from DBpedia / Wikipedia · CC BY-SA