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GeneQ17709847· pop 6· linked from 493 articles

ADCYAP1R1

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Also known as PAC1, PAC1R, PACAPR, PACAPRI, ADCYAP receptor type I

Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate cyclase activating peptide.

Gene data

ADCYAP1R1
Name
ADCYAP receptor type I
Type
protein-coding
Position
31,052,297–31,117,204 (+)
Aliases
PAC1, PAC1R, PACAPR, PACAPRI
Ensembl
ENSG00000078549
RefSeq RNA
NM_001118.5, NM_001199635.2, NM_001199636.2, NM_001199637.2, NM_001446215.1
RefSeq protein
NP_001109.2, NP_001186564.1, NP_001186565.1, NP_001186566.1, NP_001433144.1

This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010].

Gene Ontology

Pathways

cAMP signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)Circadian entrainment - Homo sapiens (human)Insulin secretion - Homo sapiens (human)Renin secretion - Homo sapiens (human)Signal TransductionSignal TransductionSignaling by NTRKsActivation of TRKA receptorsNGF-independant TRKA activation

via MyGene.info

Gene · Ensembl

ADCYAP receptor type I

Symbol
ADCYAP1R1
Biotype
Protein coding
Organism
Homo sapiens
Location
7:31,052,297-31,117,204
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
870
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/117
genomic end
31151089
genomic start
31052308
chromosome
human chromosome 7
cytogenetic location
7p14.3
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Ligands
  • References
  • Further reading
  • External links

Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC1, is a protein that in humans is encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate cyclase activating peptide.

== Function ==

Excerpted from Wikipedia’s “ADCYAP1R1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0