allysine
Sign in to saveAlso known as HCO-[CH2]3-CH(NH2)-COOH, alpha-aminoadipic delta-semialdehyde, alpha-aminoadipic acid delta-semialdehyde, 6-oxonorleucine, 2-amino-5-formylvaleric acid, DL-allysine
Allysine is a derivative of lysine that features a formyl group in place of the terminal amine. The free amino acid does not exist, but the allysine residue does. It is produced by aerobic oxidation of lysine residues by the enzyme lysyl oxidase. The transformation is an example of a post-translational modification. The semialdehyde form exists in equilibrium with a cyclic derivative. thumb|center|Conversion of lysine residue to allysine residue.|380px
Wikidata facts
- Mass
- 145.073893
Show 3 more facts
- chemical formula
- C₆H₁₁NO₃
- canonical SMILES
- C(CC=O)CC(C(=O)O)N
- Commons category
- Allysine
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Article
3 sectionsContents
- Biochemical reactions
- References
- Further reading
Allysine is a derivative of lysine that features a formyl group in place of the terminal amine. The free amino acid does not exist, but the allysine residue does. It is produced by aerobic oxidation of lysine residues by the enzyme lysyl oxidase. The transformation is an example of a post-translational modification. The semialdehyde form exists in equilibrium with a cyclic derivative. thumb|center|Conversion of lysine residue to allysine residue.|380px
==Biochemical reactions== Allysine is linked to L-lysine in reactions catalysed by saccharopine dehydrogenases. These interconvert them via saccharopine: