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alminoprofen
Sign in to saveAlso known as EB 382, 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid, p-((2-Methylallyl)amino)hydratropic acid, alpha-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid, BRN 2373633, EB-382, alminoprofene, alminoprofenum
Alminoprofen is a non-steroidal anti-inflammatory drug. the non-proprietary name alminoprofen is derived from the compound's chemical name 2-(4-[{2-methylallyl}amino]phenyl)propanic acid.
Chemical data
- Formula
- C13H17NO2
- Molecular weight
- 219.28 g/mol
- IUPAC name
- 2-[4-(2-methylprop-2-enylamino)phenyl]propanoic acid
- SMILES
- CC(C1=CC=C(C=C1)NCC(=C)C)C(=O)O
- InChIKey
- FPHLBGOJWPEVME-UHFFFAOYSA-N
- XLogP
- 3.2
- Polar surface area
- 49.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- rheumatic disease
via ChEMBL · EBI
Research
29 papers- Enantioseparation and determination of alminoprofen in rat plasma and its application to a stereoselective pharmacokinetic study.Journal of pharmaceutical and biomedical analysis · 2020
- Anti-inflammatory mechanism of alminoprofen: action on the phospholipid metabolism pathway.Biochemical pharmacology · 1999
- Pharmacological profile of alminoprofen among four writhing models of mice caused by kaolin, zymosan, acetylcholine and phenylquinone.Journal of pharmacobio-dynamics · 1990
- [Effects of alminoprofen on sodium urate crystal-induced inflammation].Nihon yakurigaku zasshi. Folia pharmacologica Japonica · 1991
- [The anti-pyretic mechanism of alminoprofen].Nihon yakurigaku zasshi. Folia pharmacologica Japonica · 1991
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 219.126
Show 5 more facts
- canonical SMILES
- CC(C1=CC=C(C=C1)NCC(=C)C)C(=O)O
- chemical formula
- C₁₃H₁₇NO₂
- subject has role
- non-steroidal anti-inflammatory drug
- World Health Organisation international non-proprietary name
- alminoprofen
- Commons category
- Alminoprofen
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Stereochemistry
- Pharmacology
- Comparison with ibuprofen
- Synthesis
- Trade names
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477318361 | IUPAC_name = 2-{4-[(2-Methylprop-2-en-1-yl)amino]phenyl}propanoic acid | image = Alminoprofen.png | image_class = skin-invert-image | image2 = Alminoprofen-3D-balls.png | image_class2 = bg-transparent
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “alminoprofen” article, available under the CC BY-SA 4.0 licence.
Gallery (3)
Available in 11 languages
via Wikidata sitelinks · CC0