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alpha,alpha-trehalose

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alpha,alpha-trehalose

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Also known as trehalose, mycose, α,α-trehalose

thumb|Crystalline trehalose dihydrate powder Trehalose is a sugar derived from two molecules of glucose. Trehalose is a disaccharide formed by a bond between two α-glucose units. It is found in nature as a disaccharide and also as a monomer in some polymers. Two other stereoisomers exist: α,β-trehalose, also called neotrehalose, and β,β-trehalose, also called isotrehalose. Neither of these alternate isomers has been isolated from living organisms, but isotrehalose has been found in starch hydroisolates. Some bacteria, fungi, plants and invertebrate animals synthesize trehalose as a source of e

Chemical data

Formula
C12H22O11
Molecular weight
342.3 g/mol
IUPAC name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol
SMILES
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O
InChIKey
HDTRYLNUVZCQOY-LIZSDCNHSA-N
XLogP
-4.2
Polar surface area
190 Ų
H-bond donors
8
H-bond acceptors
11
Formal charge
0

via PubChem

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Encyclopedic overview

11 sections
Contents
  • Synthesis
  • Properties
  • Chemical
  • Biological
  • Nutritional and dietary properties
  • Metabolism
  • Medical use
  • History
  • See also
  • References
  • External links

thumb|Crystalline trehalose dihydrate powder Trehalose is a sugar derived from two molecules of glucose. Trehalose is a disaccharide formed by a bond between two α-glucose units. It is found in nature as a disaccharide and also as a monomer in some polymers. Two other stereoisomers exist: α,β-trehalose, also called neotrehalose, and β,β-trehalose, also called isotrehalose. Neither of these alternate isomers has been isolated from living organisms, but isotrehalose has been found in starch hydroisolates. Some bacteria, fungi, plants and invertebrate animals synthesize trehalose as a source of energy, and to survive freezing and lack of water.

==Synthesis== At least three biological pathways support trehalose biosynthesis. An industrial process can derive trehalose from corn starch.

Excerpted from Wikipedia’s “alpha,alpha-trehalose” article, available under the CC BY-SA 4.0 licence.

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