筋萎縮性側索硬化症
Also known as ALS, Lou Gehrig's disease, motor neuron disease, bulbar, Lou Gehrig disease, Charcot disease, Amyotrophic lateral sclerosis, motor neurone disease, MND
筋肉の萎縮と筋力低下をもたらす神経変性疾患
AI overview
ALS (also called Lou Gehrig's disease) is a rare and serious disease where nerve cells controlling voluntary muscles gradually die, causing progressive weakness and wasting of muscles throughout the body. Over time, people with ALS lose the ability to move, speak, eat, and breathe on their own, making it a terminal condition with no cure.
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Key facts
- Medical condition.name
- Amyotrophic lateral sclerosis
- Medical condition.image
- ALS Affected neurons and muscles.png
- Medical condition.caption
- Parts of the nervous system affected by ALS, causing progressive symptoms in skeletal muscles throughout the body
- Medical condition.field
- Neurology
- Medical condition.symptoms
- Early: Stiff muscles, muscle twitches, gradual increasing weakness Late: Difficulty in speaking, swallowing, and breathing; respiratory failure; Rare: frontotemporal dementia
- Medical condition.complications
- Falling; Respiratory failure; Pneumonia; Malnutrition
- Medical condition.onset
- 45–75 years
- Medical condition.causes
- Unknown (90% to 95%) or genetic (5% to 10%)
- Medical condition.risks
Article · 日本語
筋萎縮性側索硬化症（きんいしゅくせいそくさくこうかしょう、英語: amyotrophic lateral sclerosis、略称: ALS）は、上位運動ニューロンと下位運動ニューロンの両者の細胞体が散発性・進行性に変性脱落する神経変性疾患である。運動ニューロン疾患のひとつである。ニューロンは神経単位または神経元ともよばれ、細胞体、樹状突起および軸索から構成される。筋萎縮性側索硬化症で変性する主体はニューロンの細胞体であり、軸索と樹状突起の脱落は細胞体の変化に伴う二次的な事象である。運動ニューロンの軸索変性のみでも運動ニューロン疾患と区別ができない表現形をとるがこれはニューロパチーであり運動ニューロン疾患とはいわない。
Abstract from DBpedia / Wikipedia · CC BY-SA