antiglucocorticoid
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Antiglucocorticoid drugs are a class of medications that act to reduce the effects of glucocorticoids, primarily cortisol, in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.
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Within Vinony's link graph, antiglucocorticoid is referenced by 290 other articles, and connects out to Cushing's syndrome, mometasone furoate and fludrocortisone.
It is catalogued under the topic Antiglucocorticoids.
Its subject is documented across 6 Wikipedia language editions.
~3 min read
Encyclopedic overview
6 sectionsContents
- Types
- Therapeutic applications
- Cushing's syndrome
- Psychiatric disorders
- See also
- References
Antiglucocorticoid drugs are a class of medications that act to reduce the effects of glucocorticoids, primarily cortisol, in the body. They include direct glucocorticoid receptor antagonists such as mifepristone and synthesis inhibitors such as metyrapone, ketoconazole, and aminoglutethimide. They are used to treat Cushing's syndrome.
These drugs have also been investigated for their potential therapeutic benefits in various psychiatric disorders, particularly depression and psychosis. The rationale behind using antiglucocorticoids in psychiatry stems from the observed dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in many psychiatric conditions, which often manifests as elevated cortisol levels.
Excerpted from Wikipedia’s “antiglucocorticoid” article, available under the CC BY-SA 4.0 licence.