Structure via PubChem · Public domain (PubChem)
flurandrenolide
Sign in to saveAlso known as Cordran®, flurandrenolone, Haelan®, Fludrossicortide, Fludroxycortidum, Fludroxicortide, Fludroxycortid, Fludroxycortide
Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).
In the Vinony graph
Within Vinony's link graph, flurandrenolide is referenced by 274 other articles, and connects out to mometasone furoate, fludrocortisone and ulipristal acetate.
Vinony files it under Acetonides, Corticosteroid cyclic ketals and Corticosteroids.
Its subject is documented across 12 Wikipedia language editions.
Chemical data
- Formula
- C24H33FO6
- Molecular weight
- 436.5 g/mol
- IUPAC name
- (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-one
- SMILES
- C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CO)C)O)F
- InChIKey
- POPFMWWJOGLOIF-XWCQMRHXSA-N
- XLogP
- 1.4
- Polar surface area
- 93.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1965
- Admin. routes
- topical
- Indications
- skin disease, chronic renal failure syndrome
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 436.226
- Has use
- medication
Show 5 more facts
- chemical formula
- C₂₄H₃₃FO₆
- medical condition treated
- inflammation
- subject has role
- glucocorticoid
- isomeric SMILES
- C[C@]12CCC(=O)C=C1[C@H](C[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3C[C@@H]5[C@]4(OC(O5)(C)C)C(=O)CO)C)O)F
- canonical SMILES
- CC1(OC2CC3C4CC(C5=CC(=O)CCC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C)F)C
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).
Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.
Excerpted from Wikipedia’s “flurandrenolide” article, available under the CC BY-SA 4.0 licence.