apraclonidine
Apraclonidine (INN), also known under the brand name Iopidine, is a sympathomimetic used in glaucoma therapy. It is an α2 adrenergic receptor agonist and a weak α1 adrenergic receptor agonist.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 457136476
- Drug.IUPAC_name
- 2,6-Dichloro-N- (4,5-dihydro-1H-imidazol-2-yl) benzene-1,4-diamine
- Drug.image
- Apraclonidine structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 185
- Drug.tradename
- Iopidine
- Drug.MedlinePlus
- a608005
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- Topical (ophthalmic solution)
Article
4 sectionsContents
- Medical uses
- References
- Further reading
- External links
Apraclonidine (INN), also known under the brand name Iopidine, is a sympathomimetic used in glaucoma therapy. It is an α2 adrenergic receptor agonist and a weak α1 adrenergic receptor agonist.
Topical apraclonidine is administered at a concentration of 1% for the prevention and treatment of post-surgical intraocular pressure (IOP) elevation and 0.5% for short-term adjunctive therapy in patients on maximally tolerated medical therapy who require additional reduction of IOP. One drop is usually added one hour prior to laser eye surgery and another drop is given after the procedure is complete.