Structure via PubChem · Public domain (PubChem)
bilastine
Sign in to saveAlso known as Allertine, Bilargo, Blexten, Bilaxten, Ilaxten, Nixar
Bilastine is an antihistamine medication used to treat hives (urticaria), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H1 receptor, preventing these allergic reactions. Bilastine has an effectiveness similar to cetirizine, fexofenadine, and desloratadine.
Key facts
- Drug.image
- Bilastine.svg
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 486407471
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Blexten, others
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- By mouth
- Drug.class
- Antihistamine
- Drug.ATC_prefix
- R06
- Drug.ATC_suffix
- AX29
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- /Schedule 3; Schedule 2; Appendix H, clause 1
- Drug.legal_CA
- Rx-only
- Drug.legal_NZ
- S2 (Pharmacy Only)
- Drug.bioavailability
- 61%
- Drug.protein_bound
- 84-90% binding to plasma proteins
- Drug.metabolism
- Not significantly metabolised
via Wikipedia infobox
Chemical data
- Formula
- C28H37N3O3
- Molecular weight
- 463.6 g/mol
- IUPAC name
- 2-[4-[2-[4-[1-(2-ethoxyethyl)benzimidazol-2-yl]piperidin-1-ium-1-yl]ethyl]phenyl]-2-methylpropanoate
- SMILES
- CCOCCN1C2=CC=CC=C2N=C1C3CC[NH+](CC3)CCC4=CC=C(C=C4)C(C)(C)C(=O)[O-]
- InChIKey
- ACCMWZWAEFYUGZ-UHFFFAOYSA-N
- XLogP
- 2.9
- Polar surface area
- 71.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- carboxylic acid
- Mass
- 463.283492
- Has use
- medication
Show 7 more facts
- defined daily dose
- 20
- chemical formula
- C₂₈H₃₇N₃O₃
- canonical SMILES
- CCOCCN1C2=CC=CC=C2N=C1C3CCN(CC3)CCC4=CC=C(C=C4)C(C)(C)C(=O)O
- route of administration
- oral administration
- Commons category
- Bilastine
- subject has role
- histamine antagonist
- World Health Organisation international non-proprietary name
- bilastine
Sources (3)
via Wikidata · CC0
~13 min read
Encyclopedic overview
17 sectionsContents
- Medical uses
- Allergic rhinoconjunctivitis
- Allergic rhinitis
- Urticaria
- Dosage and administration
- Side effects
- Cardiac safety
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Chemistry
- Research
- References
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 486407471 | image = Bilastine.svg | image_class = skin-invert-image | alt =
| pronounce = | tradename = Blexten, others | Drugs.com = | MedlinePlus = | pregnancy_AU = B3 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = Antihistamine | ATC_prefix = R06 | ATC_suffix = AX29 | ATC_supplemental =
Excerpted from Wikipedia’s “bilastine” article, available under the CC BY-SA 4.0 licence.