Autakoid
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Autacoids or autocoids are biological factors (molecules) which act like local hormones, have a brief duration, and act near their site of biosynthesis. The word autacoid comes from the Greek words "autos" (self) and "acos" (relief; i.e., drug). The effects of autacoids are primarily local, though large quantities can be produced and moved into circulation. Autacoids may thus have systemic effects by being transported via the circulation. These regulating molecules are also metabolized locally. In sum, these compounds typically are produced locally, act locally and are metabolized locally. Aut
Research
306,948 papers- Resolution-promoting autacoids demonstrate promising cardioprotective effects against heart diseases.Molecular biology reports · 2022
- Autacoids and control of human placental blood flow.Clinical and experimental pharmacology & physiology · 1994
- Autacoids as modulators of the inflammatory and immune response.The American journal of medicine · 1981
- Autacoids affecting vascular tone in the human fetal extracorporeal circulation.Clinical and experimental pharmacology & physiology · 1992
- Resolvins and aliamides: lipid autacoids in ophthalmology - what promise do they hold?Drug design, development and therapy · 2016
via PubMed
Wikidata facts
- Subclass of
- hormone
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- topic has template
- Template:Autacoids
Sources (2)
via Wikidata · CC0
Article · Deutsch
Als Autakoide (von griech. autos = selbst und akos = Heilmittel) werden unterschiedliche körpereigene vasoaktive Substanzen zusammengefasst. Sie können parakrin oder autokrin wirken und zu unterschiedlichen chemischen Stoffklassen gehören. Zu den Autakoiden gehören die im Endothel gebildeten vasoaktiven Substanzen und Prostaglandine, Thromboxane, Leukotriene sowie Histamin, Serotonin, Angiotensin II, Bradykinin, , und der Plättchenaktivierende Faktor. Während einige Autakoide eine wichtige Rolle bei der lokalen Durchblutungsregulation spielen, wirken andere bei entzündlichen Prozessen und bei der Blutstillung.
Abstract from DBpedia / Wikipedia · CC BY-SA