kininogen

Also known as kininogens

Kininogens are precursor proteins for kinins, biologically active polypeptides involved in blood coagulation, vasodilation, smooth muscle contraction, inflammatory regulation, and the regulation of the cardiovascular and renal systems.

Research

3,822 papers

High Molecular Weight Kininogen: A Review of the Structural Literature.International journal of molecular sciences · 2021
The kallikrein-kininogen-kinin system: lessons from the quantification of endogenous kinins.Peptides · 2000
Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis.EBioMedicine · 2020
Factor XII, kininogen and plasma prekallikrein in abnormal pregnancies.Current drug targets · 2005
[Laboratory values of kallikrein-kininogen-kinin].Nihon rinsho. Japanese journal of clinical medicine · 2005

via PubMed

~6 min read

Article

12 sections

Contents

Types of kininogen
High molecular weight kininogen
Low molecular weight kininogen
T-kininogen
Structure
Function
High-molecular weight kininogen
Low-molecular weight kininogen
T-kininogen
Disease and medical relevance
References
External links

== Types of kininogen == There are two main types of kininogen (KNG), high-molecular-weight-kininogen and low-molecular-weight-kininogen, with a third type – T-kininogen – only found in rats but not humans.