English
Structure via PubChem · Public domain (PubChem)
benzylthiouracil
Sign in to saveBenzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
Chemical data
- Formula
- C11H10N2OS
- Molecular weight
- 218.28 g/mol
- IUPAC name
- 6-benzyl-2-sulfanylidene-1H-pyrimidin-4-one
- SMILES
- C1=CC=C(C=C1)CC2=CC(=O)NC(=S)N2
- InChIKey
- PNXBXCRWXNESOV-UHFFFAOYSA-N
- XLogP
- 1.6
- Polar surface area
- 73.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
- Indications
- Abnormality of the thyroid gland
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 218.051
Show 2 more facts
- chemical formula
- C₁₁H₁₀N₂OS
- canonical SMILES
- C1=CC=C(C=C1)CC2=CC(=O)NC(=S)N2
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Adverse effects
- References
Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.
==Adverse effects== Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.
Excerpted from Wikipedia’s “benzylthiouracil” article, available under the CC BY-SA 4.0 licence.