Structure via PubChem · Public domain (PubChem)
Buserelin
Sign in to saveAlso known as buserelin acetate, HOE 766, HOE 766A, ICI 123215, Metrelef®, Suprefact®
Protein
Chemical data
- Formula
- C60H86N16O13
- Molecular weight
- 1239.4 g/mol
- IUPAC name
- (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Protein
- Indications
- neoplasm, infertility, prostate cancer, prostate adenocarcinoma
via ChEMBL · EBI
Research
2,571 papers- Buserelin. A review of its pharmacodynamic and pharmacokinetic properties, and clinical profile.Drugs · 1990
- [Buserelin].Deutsche medizinische Wochenschrift (1946) · 1994
- Buserelin in the treatment of prostatic cancer.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 1989
- Buserelin Promotes the Differentiation and Function of Macrophage-Colony-Stimulating Factor-Producing T Helper Cells.Immunological investigations · 2025
- Buserelin Inhibits the Immunosuppressive Activity of Regulatory T Cells through the Protein Kinase A Signaling in a Central Precocious Puberty Model.Immunological investigations · 2022
via PubMed
Wikidata facts
- Mass
- 1238.656027
- Has use
- medication
Show 5 more facts
- chemical formula
- C₆₀H₈₆N₁₆O₁₃
- canonical SMILES
- CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(COC(C)(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6
- isomeric SMILES
- CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
- defined daily dose
- 1.5
- has characteristic
- biopharmaceutical
Sources (3)
via Wikidata · CC0
Article · Deutsch
Buserelin ist die Abkürzung für Butylserylrelin und beschreibt einen hormonell wirksamen Arzneistoff, der als GnRH-Analogon wirkt.
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 11 languages
via Wikidata sitelinks · CC0