Butacaine is a white crystalline ester used as a local anesthetic. It was first marketed in the 1920s.
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Butacaine is a white crystalline ester used as a local anesthetic. It was first marketed in the 1920s.
==Synthesis== The addition of metallic sodium to a mixture of allyl alcohol (1) and dibutylamine (2) gives the conjugate addition product 3-dibutylamino-1-propanol (3). Reaction of this intermediate with p-nitrobenzoyl chloride (4) gives the ester 5. A Béchamp reduction of the nitro group completes the synthesis of butacaine (6). thumb|500px|center|Synthesis of butacaine
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).