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GeneQ18033157· pop 5· linked from 5 articles

Also known as CADPS1, CAPS, CAPS1, UNC-31, Ca2+ dependent secretion activator, calcium dependent secretion activator

Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.

Gene data

CADPS
Name
calcium dependent secretion activator
Type
protein-coding
Aliases
CADPS1, CAPS, CAPS1, UNC-31

This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008].

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Wikidata facts

Image
Protein CADPS PDB 1wi1.png
Show 5 more facts
HomoloGene ID
2755
genomic end
62875416
genomic start
62384022
cytogenetic location
3p14.2
Sources (4)

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Calcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.

CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. CADPS acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.

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