CDH17
Sign in to saveAlso known as CDH16, HPT-1, HPT1, cadherin 17
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
Gene data
CDH17- Name
- cadherin 17
- Type
- protein-coding
- Position
- 94,124,381–94,217,303 (−)
- Aliases
- CDH16, HPT-1, HPT1
- Ensembl
- ENSG00000079112
- RefSeq RNA
- NM_001144663.2, NM_001413951.1, NM_001413952.1, NM_001413953.1, NM_001413954.1
- RefSeq protein
- NP_001138135.1, NP_001400880.1, NP_001400881.1, NP_001400882.1, NP_001400883.1
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cadherin 17
- Symbol
- CDH17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:94,124,381-94,217,303
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Cadherin-17 is a protein that in humans is encoded by the CDH17 gene.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.
Excerpted from Wikipedia’s “CDH17” article, available under the CC BY-SA 4.0 licence.