TACSTD2
Sign in to saveAlso known as EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2, tumor-associated calcium signal transducer 2
Tumor-associated calcium signal transducer 2, also known as Trop-2 and as epithelial glycoprotein-1 antigen (EGP-1) is a protein that in humans is encoded by the TACSTD2 gene.
Gene data
TACSTD2- Name
- tumor associated calcium signal transducer 2
- Type
- protein-coding
- Aliases
- EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009].
via MyGene.info
Wikidata facts
- Image
- TACSTD2.png
Show 5 more facts
- HomoloGene ID
- 1763
- exact match
- identifiers.org/ncbigene/4070
- genomic end
- 58577252
- genomic start
- 58575433
- cytogenetic location
- 1p32.1
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Article
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- Further reading
Tumor-associated calcium signal transducer 2, also known as Trop-2 and as epithelial glycoprotein-1 antigen (EGP-1) is a protein that in humans is encoded by the TACSTD2 gene.
This intronless gene is located at the short arm of chromosome 1 (1p32.1). It encodes a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor.