CALCR
Sign in to saveAlso known as CRT, CT-R, CTR, CTR1, calcitonin receptor
protein-coding gene in the species Homo sapiens
Gene data
CALCR- Name
- calcitonin receptor
- Type
- protein-coding
- Position
- 93,424,486–93,575,738 (−)
- Aliases
- CRT, CT-R, CTR, CTR1
- Ensembl
- ENSG00000004948
- RefSeq RNA
- NM_001164737.3, NM_001164738.2, NM_001742.4
- RefSeq protein
- NP_001158209.2, NP_001158210.1, NP_001733.1
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
cell surface receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwaypositive regulation of cytosolic calcium ion concentration
Molecular function
Pathways
Neuroactive ligand-receptor interaction - Homo sapiens (human)Osteoclast differentiation - Homo sapiens (human)Signal TransductionSignaling by GPCRClass B/2 (Secretin family receptors)GPCR downstream signallingG alpha (s) signalling eventsCalcitonin-like ligand receptorsGPCR ligand bindingRANKL-RANK signaling pathway
via MyGene.info
Gene · Ensembl
calcitonin receptor
- Symbol
- CALCR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:93,424,486-93,575,738
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 1320
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/799
- genomic end
- 93204042
- genomic start
- 93424486
- chromosome
- human chromosome 7
- cytogenetic location
- 7q21.3
- expressed in
- tendon
- Commons category
- Calcitonin receptor
via Wikidata · CC0
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via Wikidata sitelinks · CC0