File:Cannabidiol.svg · Wikimedia Commons · See Wikimedia Commons
cannabidiol
Sign in to saveAlso known as CBD, GWP42003-P, 1,3-benzenediol, 2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)-5-pentyl-, (1R,6R)-
Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in Cannabis, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. Medically, it is an anticonvulsant used to treat two rare forms of childhood epilepsy. It was discovered in 1940. Clinical research on CBD has included studies related to the treatment of anxiety, addiction, psychosis, movement disorders, and pain, but there is insufficient high-quality evidence that CBD is effective for these conditions. CBD is sold as a herbal dietary supplement and promoted with unproven claims of
OverviewAI-generated
Cannabidiol is a chemical compound with the formula C₂₁H₃₀O₂. Its IUPAC name is 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol. The substance has a mass of 314.22458 and a melting point of 66.
Chemical properties include an xlogp of 6.5 and a topological polar surface area of 40.5. The molecule contains two hydrogen bond donors and two hydrogen bond acceptors, with a charge of 0. PubChem lists its weight as 314.5.
Literature on cannabidiol includes 8,810 entries in PubMed. The subject is referenced by 3,316 other encyclopedia articles.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.image
- Cannabidiol Structural formula V1.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 280
- Drug.image2
- D2CBD 3D-BALL-AND-STICK.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Epidiolex, Epidyolex
- Drug.MedlinePlus
- a618051
- Drug.DailyMedID
- Cannabidiol
- Drug.pregnancy_AU
- B2
- Drug.addiction_liability
- None
- Drug.routes_of_administration
- By mouth, sublingual, buccal, inhalation
- Drug.class
- Cannabinoid
- Drug.ATC_prefix
- N03
- Drug.ATC_suffix
- AX24
- Drug.legal_AU
- S4
- Drug.legal_BR
- Synthetic: C3; Oil with <0,2% THC: B1; Oil <30mg/ml THC and <30mg/ml CBD: A3.
- Drug.legal_CA
- Unscheduled
via Wikipedia infobox
Chemical data
- Formula
- C21H30O2
- Molecular weight
- 314.5 g/mol
- IUPAC name
- 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
- SMILES
- CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O
- InChIKey
- QHMBSVQNZZTUGM-ZWKOTPCHSA-N
- XLogP
- 6.5
- Polar surface area
- 40.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
8,810 papers- Endometriosis: cannabidiol therapy for symptom relief.Trends in pharmacological sciences · 2024
- Cannabidiol Adverse Effects and Toxicity.Current neuropharmacology · 2019
- Scientific Validation of Cannabidiol for Management of Dog and Cat Diseases.Annual review of animal biosciences · 2023
- Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.The New England journal of medicine · 2018
- Cannabidiol and epilepsy.International review of neurobiology · 2024
via PubMed
~37 min read
Encyclopedic overview
48 sectionsContents
- Medical uses
- Epilepsy
- Antimicrobial property
- Other uses
- Non-intoxicating effects
- Available forms
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Overview
- Biosynthesis
- Isomerism
- Pyrolysis
- Synthetic derivatives
- History
- Plant breeding
- Society and culture
- Names
- Foods and beverages
- Labeling and advertising
- Sports
- Legal status
- Australia
- Canada
- European Union
- Bulgaria
- Czech Republic
- Sweden
- Hong Kong
- New Zealand
- Russian Federation
- Singapore
- Switzerland
- Ukraine
- United Kingdom
- United Nations
- United States
- Veterinary use
- Research
- Canine osteoarthritis
- Epilepsy
- Pharmacokinetics
- Research
- References
- Further reading
Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in Cannabis, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. Medically, it is an anticonvulsant used to treat two rare forms of childhood epilepsy. It was discovered in 1940. Clinical research on CBD has included studies related to the treatment of anxiety, addiction, psychosis, movement disorders, and pain, but there is insufficient high-quality evidence that CBD is effective for these conditions. CBD is sold as a herbal dietary supplement and promoted with unproven claims of particular therapeutic effects.
Cannabidiol can be taken internally in multiple ways, including by inhaling cannabis smoke or vapor, swallowing it by mouth, and through use of an aerosol spray inside the cheek. It may be supplied as CBD oil containing only CBD as the active ingredient (excluding THC or terpenes), CBD-dominant hemp extract oil, capsules, dried cannabis, or prescription liquid solution. CBD does not have the same psychoactivity as THC, and can modulate the psychoactive effects of THC on the body if both are present. Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C, potentially leading to its partial transformation into THC.
Excerpted from Wikipedia’s “cannabidiol” article, available under the CC BY-SA 4.0 licence.