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Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C15H19N3O5
- Molecular weight
- 321.33 g/mol
- IUPAC name
- [2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl] carbamate
- SMILES
- CC1=C(C(=O)C(=C(C1=O)N2CC2)C(COC(=O)N)OC)N3CC3
- InChIKey
- SHHKQEUPHAENFK-UHFFFAOYSA-N
- XLogP
- -0.2
- Polar surface area
- 102 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- neoplasm
via ChEMBL · EBI
Research
276 papers- [An anticancer drug--carboquone].Gan to kagaku ryoho. Cancer & chemotherapy · 1988
- Carboquone therapy for hematologic neoplasms.The Tohoku journal of experimental medicine · 1982
- Treatment of multiple myeloma with carboquone-prednisolone.European journal of haematology · 1989
- Detection of DNA strand breaks in HeLa cells in vitro and in mouse sarcoma 180 cells in vivo induced by an alkylating agent, carboquone, using in situ nick translation.Oncology · 1990
- Interaction of antitumor agents including carboquone in sarcoma-180 system.Gan · 1976
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 321.132
- Has use
- medication
Show 3 more facts
- chemical formula
- C₁₅H₁₉N₃O₅
- canonical SMILES
- CC1=C(C(=O)C(=C(C1=O)N2CC2)C(COC(=O)N)OC)N3CC3
- subject has role
- alkylating antineoplastic agent
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- See also
{{Drugbox | Watchedfields = changed | verifiedrevid = 444188235 | IUPAC_name = {2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl} carbamate | image = Carboquone.png | image_class = skin-invert-image
| tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “carboquone” article, available under the CC BY-SA 4.0 licence.
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