CASC3
Sign in to saveAlso known as BTZ, MLN51, cancer susceptibility candidate 3, cancer susceptibility 3, CASC3, exon junction complex subunit, CASC3 exon junction complex subunit
Protein CASC3 is a protein that in humans is encoded by the CASC3 gene.
In the Vinony graph
Within Vinony's link graph, CASC3 is referenced by 3 other articles, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CASC3- Name
- CASC3 exon junction complex subunit
- Type
- protein-coding
- Position
- 40,140,278–40,177,001 (+)
- Aliases
- BTZ, MLN51
- Ensembl
- ENSG00000108349
- RefSeq RNA
- NM_007359.5, XM_005257163.3, XM_047435623.1, XM_047435624.1, XM_054315480.1
- RefSeq protein
- NP_031385.2, XP_005257220.1, XP_047291579.1, XP_047291580.1, XP_054171455.1
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CASC3 exon junction complex subunit
- Symbol
- CASC3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:40,140,278-40,177,001
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- The crystal structure of the human Exon Junction Complex 2J0S CASC3.png
Show 7 more facts
- HomoloGene ID
- 7208
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/22794
- genomic end
- 40172171
- genomic start
- 38296571
- chromosome
- human chromosome 17
- cytogenetic location
- 17q21.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- External links
- Further reading
Protein CASC3 is a protein that in humans is encoded by the CASC3 gene.
== Function ==
Excerpted from Wikipedia’s “CASC3” article, available under the CC BY-SA 4.0 licence.