In the Vinony graph
Within Vinony's link graph, CAST is referenced by 7 other articles, and connects out to PubMed, human chromosome 5 and Ensembl genome database project.
Vinony files it under EC 3.4, Genes on human chromosome 5 and Proteases.
Its subject is documented across 8 Wikipedia language editions.
Gene data
CAST- Name
- calpastatin
- Type
- protein-coding
- Aliases
- BS-17, MIR583HG, PLACK
The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].
via MyGene.info
Gene · Ensembl
calpastatin
- Symbol
- CAST
- Biotype
- LncRNA
- Organism
- Homo sapiens
- Location
- 5:95,962,001-96,631,085
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7658
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/831
- genomic end
- 96115299
- genomic start
- 95860971
- chromosome
- human chromosome 5
- cytogenetic location
- 5q15
via Wikidata · CC0