Also known as cluster of differentiation 1, Antigens, CD1
CD1 (cluster of differentiation 1) is a family of glycoproteins expressed on the surface of various human antigen-presenting cells. CD1 glycoproteins are structurally related to the class I MHC molecules, however, in contrast to MHC class 1 proteins, they present lipids, glycolipids and small molecules antigens, from both endogenous and pathogenic proteins, to T cells and activate an immune response.
Key facts
- Protein.Arm
- q
- Protein.Band
- 22
- Protein.Name
- CD1e molecule
- Protein.HGNCid
- 1638
- Protein.Symbol
- CD1E
- Protein.AltSymbols
- CD1
- Protein.EntrezGene
- 913
- Protein.OMIM
- 188411
- Protein.RefSeq
- NM_030893
- Protein.UniProt
- P15812
- Protein.Chromosome
- 1
- Protein.LocusSupplementaryData
- -q23
via Wikipedia infobox
Research
13,820 papersvia PubMed
Article · 日本語
CD1は種々の抗原提示細胞の表面に発現している糖タンパク質、細胞表面抗原の1つである。この分子は1型の主要組織適合抗原 (MHC-1) と深く関連し、T細胞への脂質抗原の提示に関わる。しかしながら、詳しい機能は知られていない。
Abstract from DBpedia / Wikipedia · CC BY-SA