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EntityQ78482053· pop 10· linked from 408 articles

كتلة التمايز 16

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CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, macrophages, and certain T cells. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in triggering lysis by NK cells, CD16 is a molecule of the immunoglobulin superfamily (IgSF) involved in antibody-dependent cellular cytotoxicity (ADCC). It can be used to isolate populations of specific immune cells through fluorescent-activated cel

Key facts

Protein.HGNCid
3619
Protein.Name
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
Protein.Symbol
FCGR3B
Protein.AltSymbols
FCGR3, FCG3
Protein.EntrezGene
2215
Protein.OMIM
610665
Protein.RefSeq
NM_000570
Protein.UniProt
O75015
Protein.Chromosome
1
Protein.Arm
q
Protein.Band
23

via Wikipedia infobox

Wikidata facts

Instance of
protein family
Show 1 more fact
Commons category
CD16
Sources (2)

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Article · العربية

كتلة التمايز 16 (بالإنجليزية: Cluster of Differentiation 16)‏هو أحد مستقبلات Fc. يتواجد هذا البروتين على سطح الخلايا الفاتكة الطبيعية، الخلايا المتعادلة، الخلايا الوحيدة، والبلعميات. تم اكتشاف أن المستقبلان (FcγRIIIa (CD16a و(FcγRIIIb (CD16b يشكلان كتلة التمايز هذه، وأنهما يشاركا في توصيل الإشارة. يقوم هذا المستقبل في الخلايا الفاتكة الطبيعية بابتداء .

Abstract from DBpedia / Wikipedia · CC BY-SA

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