Also known as LEU1, T1, CD5 molecule
gen de la especie Homo sapiens
Gene data
CD5- Name
- CD5 molecule
- Type
- protein-coding
- Position
- 61,102,466–61,127,952 (+)
- Aliases
- LEU1, T1
- Ensembl
- ENSG00000110448
- RefSeq RNA
- NM_001346456.2, NM_014207.4
- RefSeq protein
- NP_001333385.1, NP_055022.2
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CD5 molecule
- Symbol
- CD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:61,102,466-61,127,952
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CD5 (PBB).jpg
Show 8 more facts
- HomoloGene ID
- 7260
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/921
- genomic end
- 60895324
- genomic start
- 61102489
- chromosome
- human chromosome 11
- cytogenetic location
- 11q12.2
- expressed in
- thymus
via Wikidata · CC0
Article · Español
En inmunología se denomina CD5 (del inglés cluster of differentiation) a un tipo de antígeno CD propio del sistema inmune de mamíferos. Se caracteriza por poseer un peso molecular de 55 kDa y su naturaleza bioquímica lo encuadra dentro de la familia de receptores basurero. Su función biológica en la célula es: mediar en la transducción de señal, mitigando la respuesta inmune ante sustancias que no deban desencadenar aquella. Se expresa específicamente en timocitos, células T y subpoblaciones de células B (las secretoras de IgM).
Abstract from DBpedia / Wikipedia · CC BY-SA