Structure via PubChem · Public domain (PubChem)
cefonicid
Sign in to saveAlso known as (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, Cefonicido, Cefonicidum
Cefonicide (or cefonicid) is a cephalosporin antibiotic.
In the Vinony graph
Vinony's link graph records 190 inbound references to cefonicid, and connects out to antibiotic, ceftolozane/tazobactam and penicillin.
It is catalogued under topics including Acetaldehyde dehydrogenase inhibitors, Cephalosporin antibiotics and Chemical pages without DrugBank identifier.
Vinony links it to 14 Wikipedia language editions.
Chemical data
- Formula
- C18H18N6O8S3
- Molecular weight
- 542.6 g/mol
- IUPAC name
- (6R,7R)-7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)O)C(=O)O)CSC4=NN=NN4CS(=O)(=O)O
- InChIKey
- DYAIAHUQIPBDIP-AXAPSJFSSA-N
- XLogP
- -1.9
- Polar surface area
- 264 Ų
- H-bond donors
- 4
- H-bond acceptors
- 13
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1984
- Admin. routes
- parenteral
- Indications
- osteomyelitis, bacterial disease
via ChEMBL · EBI
Research
256 papers- Cefonicid. A review of its antibacterial activity, pharmacological properties and therapeutic use.Drugs · 1986
- Cephalosporins.2012
- Cefonicid: a long-acting, second-generation cephalosporin. Antimicrobial activity, pharmacokinetics, clinical efficacy and adverse effects.Pharmacotherapy · 1984
- Review of cefonicid, a long-acting cephalosporin.Clinical pharmacy · 1984
- Cefonicid: a stable beta-lactamase inhibitor.The Journal of antibiotics · 1981
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 542.034825
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₈H₁₈N₆O₈S₃
- Commons category
- Cefonicid
- canonical SMILES
- C1C(=C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)O)C(=O)O)CSC4=NN=NN4CS(=O)(=O)O
- isomeric SMILES
- C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)O)C(=O)O)CSC4=NN=NN4CS(=O)(=O)O
- World Health Organisation international non-proprietary name
- cefonicid
- defined daily dose
- 1
- subject has role
- bactericide
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
{{Drugbox | Watchedfields = changed | verifiedrevid = 443509375 | IUPAC_name = (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetyl)amino]-8-oxo-3-{[1-(sulfomethyl)tetrazol-5-yl]sulfanylmethyl}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = cefonicid.png | image_class = skin-invert-image
| tradename = | Drugs.com = | MedlinePlus = a601206 | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “cefonicid” article, available under the CC BY-SA 4.0 licence.
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