CES1

Name

carboxylesterase 1

Type

protein-coding

Position

55,802,845–55,833,337 (−)

Aliases

ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH

Ensembl

ENSG00000262243

RefSeq RNA

NM_001025194.2, NM_001025195.2, NM_001266.5, XM_005255774.3, XM_054329577.1

RefSeq protein

NP_001020365.1, NP_001020366.1, NP_001257.4, XP_005255831.1, XP_054185552.1

This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

via MyGene.info

Gene · Ensembl

carboxylesterase 1

Symbol

CES1

Biotype

Protein coding

Organism

Homo sapiens

Location

16:55,802,845-55,833,337

Strand

Reverse (−)

Assembly

GRCh38