CGP7930
Sign in to saveAlso known as CGP 7930, CGP-7930
CGP-7930 was the first positive allosteric modulator of GABAB receptors described in literature. CGP7930 is also a GABAA receptor positive allosteric modulator and a blocker of Potassium channels.
Wikidata facts
- Mass
- 292.24023
Show 2 more facts
- chemical formula
- C₁₉H₃₂O₂
- canonical SMILES
- CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC(C)(C)CO
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Article
3 sectionsContents
- Synthesis
- See also
- References
CGP-7930 was the first positive allosteric modulator of GABAB receptors described in literature. CGP7930 is also a GABAA receptor positive allosteric modulator and a blocker of Potassium channels.
CGP7930 was developed in Novartis and has been used extensively for scientific research. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists such as baclofen and GHB, as well as reducing self-administration of alcoholic drinks and cocaine.
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