chlorpyrifos
Sign in to saveChlorpyrifos (CPS), also known as chlorpyrifos ethyl, is an organophosphate pesticide that has been used on crops, animals, in buildings, and in other settings, to kill several pests, including insects and worms. It acts on the nervous systems of insects by inhibiting the acetylcholinesterase enzyme. Chlorpyrifos was patented in 1966 by Dow Chemical Company.
Research
7,427 papers- Ecotoxicology of chlorpyrifos.Reviews of environmental contamination and toxicology · 1995
- Biodegradation of chlorpyrifos pollution from contaminated environment - A review on operating variables and mechanism.Environmental research · 2024
- Chlorpyrifos and neuroendocrine function: Concerns for research with free-living mammal populations.General and comparative endocrinology · 2025
- Insights into the microbial degradation and catalytic mechanisms of chlorpyrifos.Environmental research · 2021
- Chlorpyrifos and Chlorpyrifos-Oxon: A Widening Spectrum of Toxicity.International journal of molecular sciences · 2026
via PubMed
Article
45 sectionsContents
- Synthesis
- Uses
- Application
- Kinetics
- Mechanism of action
- Human toxicity
- Acute health effects
- Symptoms of acute exposure
- Frequency of acute exposure
- Treatment
- Tourist deaths
- Long term
- Development
- Adulthood
- Chlorpyrifos methyl
- Mechanisms of toxicity
- Acetylcholine neurotransmission
- Non-cholinesterase mechanisms
- Paraoxonase activity
- Combined exposures
- Human exposure
- Effects on wildlife
- Aquatic life
- Bees
- Regulation
- International law
- National regulations
- United States
- Residue
- Water
- Reporting
- Occupational exposure
- State laws
- Australia
- Denmark
- European Union
- India
- New Zealand
- Thailand
- Malaysia
- Uganda
- Manufacture
- See also
- References
- External links
Chlorpyrifos (CPS), also known as chlorpyrifos ethyl, is an organophosphate pesticide that has been used on crops, animals, in buildings, and in other settings, to kill several pests, including insects and worms. It acts on the nervous systems of insects by inhibiting the acetylcholinesterase enzyme. Chlorpyrifos was patented in 1966 by Dow Chemical Company.
Chlorpyrifos is considered moderately hazardous to humans (Class II) by the World Health Organization based on acute toxicity information dating to 1999. Exposure surpassing recommended levels has been linked to neurological effects, persistent developmental disorders, and autoimmune disorders. Exposure during pregnancy may harm the mental development of children.