choriocarcinoma

Also known as chorioblastoma, chorionic carcinoma, chorion carcinoma, choriocarcinoma, no ICD-O subtype (morphologic abnormality), chorioepithelioma, chorioepithelioma NOS

Choriocarcinoma is a trophoblastic cancer usually located on the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.

Key facts

Medical condition (new).caption: Micrograph of choriocarcinoma showing both of the components necessary for the diagnosis – cytotrophoblasts and syncytiotrophoblasts. The syncytiotrophoblasts are multinucleated and have a dark staining cytoplasm. The cytotrophoblasts are mononuclear and have a pale staining cytoplasm. H&E stain.
Medical condition (new).field: Oncology
Medical condition (new).name: Choriocarcinoma
Medical condition (new).image: Choriocarcinoma -2- very high mag.jpg

via Wikipedia infobox

Research

10,694 papers

[Choriocarcinoma].Ginekologia polska · 1995
Non-gestational choriocarcinoma: unraveling the similarities and distinctions from its gestational counterpart.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024
[Choriocarcinoma].Medizinische Klinik · 1975

Article

6 sections

Contents

Signs and symptoms
Cause
Pathology
Treatment
References
External links

==Signs and symptoms== increased quantitative chorionic gonadotropin (the "pregnancy hormone") levels vaginal bleeding shortness of breath hemoptysis (coughing up blood) chest pain chest X-ray shows multiple infiltrates of various shapes in both lungs presents in males as a testicular cancer, sometimes with skin hyperpigmentation (from excess chorionic gonadotropin cross-reacting with the alpha MSH receptor), gynecomastia, and weight loss (from excess chorionic gonadotropin cross-reacting with the LH, FSH, and TSH receptor) in males can present with decreased thyroid-stimulating hormone (TSH) due to hyperthyroidism.