clebopride
Sign in to saveClebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.
Chemical data
- Formula
- C20H24ClN3O2
- Molecular weight
- 373.9 g/mol
- IUPAC name
- 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide
via PubChem
Research
158 papers- Clebopride-Associated Movement Disorders.Movement disorders clinical practice · 2023
- Clebopride stimulates 5-HT(4)-serotonin receptors in the human atrium.Naunyn-Schmiedeberg's archives of pharmacology · 2025
- [Clebopride].Giornale di clinica medica · 1988
- Efficacy and Safety of Drugs for Gastroparesis: Systematic Review and Network Meta-analysis.Gastroenterology · 2023
- Clebopride enhances contractility of the guinea pig stomach by blocking peripheral D2 dopamine receptor and alpha-2 adrenoceptor.The Journal of pharmacology and experimental therapeutics · 1991
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +373.156
Show 1 more fact
- P2868
- antiemetic
via Wikidata · CC0
Article
1 sectionsContents
- References
Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide.
A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.