Structure via PubChem · Public domain (PubChem)
clonixin
Sign in to saveAlso known as SCH-10304, Sch 10304, Clonixic acid, 2-(3-Chloro-o-toluidino)nicotinic acid, 2-(2'-Methyl-3'-chloro)anilinonicotinic acid, CBA 93626, 2-(3-Chloro-2-methylanilino)nicotinic acid
Clonixin is a nonsteroidal anti-inflammatory drug (NSAID). It also has analgesic, antipyretic, and platelet-inhibitory actions. It is used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
Chemical data
- Formula
- C13H11ClN2O2
- Molecular weight
- 262.69 g/mol
- IUPAC name
- 2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid
- SMILES
- CC1=C(C=CC=C1Cl)NC2=C(C=CC=N2)C(=O)O
- InChIKey
- CLOMYZFHNHFSIQ-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 62.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
717 papers- Toxic influence.Nature · 2014
- Repurposing clonixin and flunixin as anti-fibrotic candidates: Computational and preclinical evaluation in bleomycin-induced pulmonary fibrosis in rats.Research in veterinary science · 2025
- Interaction of clonixin with EPC liposomes used as membrane models.Journal of pharmaceutical sciences · 2005
- Effect of clonixin and aspirin on platelet aggregation in human volunteers.Journal of clinical pharmacology · 1976
- Determination of clonixin in plasma and urine by reversed-phase high-performance liquid chromatography.Journal of chromatography. A · 2000
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 262.051
- Has use
- medication
Show 6 more facts
- has characteristic
- bitterness
- chemical formula
- C₁₃H₁₁ClN₂O₂
- canonical SMILES
- CC1=C(C=CC=C1Cl)NC2=C(C=CC=N2)C(=O)O
- World Health Organisation international non-proprietary name
- clonixin
- subject has role
- non-steroidal anti-inflammatory drug
- medical condition treated
- migraine
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Synthesis
- Clonixeril
- See also
- References
Clonixin is a nonsteroidal anti-inflammatory drug (NSAID). It also has analgesic, antipyretic, and platelet-inhibitory actions. It is used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
==Synthesis== class=skin-invert-image|thumb|center|700px|Clonixin synthesis: M. H. Sherlock, N. Sperber, ; eidem, (1966, 1967 both to Schering-Plough|Schering).
Excerpted from Wikipedia’s “clonixin” article, available under the CC BY-SA 4.0 licence.